Optimalisasi Proses Monkey Neurovirulence Test (MNVT) pada Produksi Vaksin Polio di PT XYZ dengan Pendekatan Lean Manufacturing
DOI:
https://doi.org/10.33197/jlscc.v4i1.3062Keywords:
Waste, Kaizen, Monkey Neurovirulence Test, Value Stream MappingAbstract
PT XYZ is a national pharmaceutical company that produces various vaccines, including the polio vaccine. The polio vaccine production process involves a crucial stage, the Monkey Neurovirulence Test (MNVT), to ensure the vaccine is safe and does not cause damage to nerve tissue, in accordance with WHO guidelines. However, based on QC Time data from December 2023–2024, the average polio vaccine testing time reached 192 days per batch, exceeding the maximum time of 140 days. This study aims to analyze MNVT testing activities, analyze the factors causing waste, and provide improvement suggestions. The methods used were Lean Manufacturing with Value Stream Mapping (VSM), VALSAT, the Borda method to determine dominant waste, and the Kaizen approach. The results showed that dominant waste was in the form of waiting (weighted 0.24) and defects (weighted 0.21). The majority of activities were classified as NNVA (57%) and NVA (2%), with delay activities reaching 52%. Suggested improvements included tissue processor optimization, weekly evaluations, and skill matrix training. The implementation of improvements reduced the total testing process time from 191 to 186 days. This reduction indicates increased process efficiency, which is expected to support the achievement of quality assurance time and polio vaccine testing capacity at PT XYZ.
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